José Salgado-Borges

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Several refractive and therapeutic treatments as well as several ocular or systemic diseases might induce changes in the mechanical resistance of the cornea. Furthermore, intraocular pressure measurement, one of the most used clinical tools, is also highly dependent on this characteristic. Corneal biomechanical properties can be measured now in the clinical(More)
PURPOSE The purpose of this study was to compare a new scleral fixation foldable intraocular lens (IOL), the Ophtec PC 425Y 6/13.5, with the scleral fixation rigid IOL Alcon CZ 70 BD, as regards efficacy, surgical complications, advantages, disadvantages, and surgery costs in cases with no capsule support. MATERIAL AND METHODS This was a retrospective(More)
PURPOSE To study the perception of light distortion after refractive lens exchange (RLE) with diffractive multifocal intraocular lenses (IOLs). SETTING Clínica Oftalmológica das Antas, Porto, Portugal. DESIGN Retrospective comparative study. METHODS Refractive lens exchange was performed with implantation of an AT Lisa 839M (trifocal) or 909MP(More)
Corneal collagen crosslinking (CXL) is a promising new treatment modality designed to stabilize or decrease the progression of keratoconus, as well as other corneal-thinning processes such as ectasia after LASIK or PRK. An increase in corneal biomechanical strength after CXL slows the progression of keratoconus and other forms of ectasia with few reported(More)
Purpose. To determine whether the retinal pigment epithelium (RPE) exhibits any substantial phototoxicity and, if so, which arc the major cbromophorcs involved. M&o&. Intact human RF'E cells were isolated from the posterior poles of human and bovine eyes. Lipofoscm and melanosome granules were also isolated from human donor eyes. Action spectra of oxygen(More)
Purpose. To compare the characteristics of asymmetric keratoconic eyes and normal eyes by Fourier domain optical coherence tomography (OCT) corneal mapping. Methods. Retrospective corneal and epithelial thickness OCT data for 74 patients were compared in three groups of eyes: keratoconic (n = 22) and normal fellow eyes (n = 22) in patients with asymmetric(More)
w The human wrnea is a densely innervated struchxe. However, data on nerve fiber (NF) distribution in tbe human cornea are scarce possibly due to fast post mortem degeneration. Therefore, moat descriptions on comeal innervation are based on studies in rats and rabbits. Tbe present study is focussed on the ulaastruaure of NF's in the central and peripheral(More)
We determined the effects of cocaine hydrochloride (15 mg/kg body weight/day) or amphetamine sulfate (25 mg/kg body weight/day) on the optic nerve in groups of rats exposed from postnatal day 1 to 30. Qualitative and quantitative studies of cross-sections of the optic nerves showed different patterns of organization, namely the presence of degenerative(More)
Puroose: The present study investigated whether flupirtine, a non-opioid analgesic agent with some NMDA antagonistic properties in viva and in vitro, protects from ischaemic retinal injury. Methods and Results: Retinal ischaemia was induced either by transient occlusion of both common carotid arteries in the rat or by a " suction cup procedure " which(More)