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This paper studies the influence exerted by the presynaptic spike train on the postsynaptic one. It applies to synaptic exploration a novel method for characterization of point-process systems (Brillinger, 1974, 1975a), and draws from it physiologically meaningful conclusions. The departure point was a large data set of action potential trains from an(More)
1. Those features of a transmembrane current correlated with spike initiation were examined in Aplysia neurones using a Gaussian white-noise stimulus. This stimulus has the advantages that it presents numerous wave forms in random order without prejudgement as to their efficacies, and that it allows straightforward statistical calculations. 2. Stimulation(More)
An elementary model of neuronal activity involves temporal and spatial summation of postsynaptic currents that are elicited by presynaptic spikes and that, in turn, elicit postsynaptic potentials at a trigger zone; when the potential at the trigger zone exceeds a "threshold" level, a postsynaptic spike is generated. This paper describes three methods of(More)
Different synaptic terminals of the single excitor axon to the opener muscle of crayfish (Procambarus clarkii) often release transmitter in a very different manner when stimulated with the same equal-interval, doublet, or triplet patterns. Compared to synapses that show little facilitation (low Fe synapses), highly facilitating (high Fe) synapses show(More)
2. Coding depends on numerous variables (e.g., synaptic type, discharges involved). Discharge variabilities have simplifying influences. 3. In addition to discharge assimilation to point processes, formal issues with physiological implications include, the neuron's analyzer role, the definition ofcoding, and probab-ilistic and informational aspects. Linking(More)
This communication describes the new information that may be obtained by applying nonlinear analytical techniques to neurobiological time-series. Specifically, we consider the sequence of interspike intervals Ti (the "timing") of trains recorded from synaptically inhibited crayfish pacemaker neurons. As reported earlier, different postsynaptic spike train(More)
  • David R Brillinger, J P Segundo, Ruiz Bryant, Segundo Marcos, Se Bryant
  • 2014
Collections of occurrence times of events taking place irregularly in time provide a fairly common, but not broadly discussed, data type. This article is concerned with the particular circumstance of firing times in nerve cells that interact and form networks. The article reviews a progression of statistical analysis techniques: description, association as(More)
The presynaptic fiber at an inhibitory synapse on a pacemaker neuron was forced to generate transients, defined here as spike trains with a trend, unceasingly accelerating or slowing. Experiments were on isolated crayfish stretch receptor organs. Spike train analyses used tools and notions from conventional point processes and from non-linear dynamics. Pre-(More)