José Miguel Laínez

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Keywords: Supply chain management Product portfolio management Supplier–customer relationships Corporate value Inventory management Risk management Flexibility a b s t r a c t Enterprise-wide decision problems are receiving increasing attention in the process systems engineering literature. In particular, the supply chain and product development pipeline(More)
The FDA's Quality by Design initiative and associated design space construct (ICH, 2009), have stimulated the use of quantitative methods, mathematical and statistical models, and designed experiments in the process of drug development and manufacture. For a given drug product , the design space may be interpreted as the constrained region of the(More)