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This study was designed to evaluate the protective effect of amifostine on indomethacin-induced gastric damage, and the role of increased gastric non-protein sulfhydryl groups (NP-SH) and decreased(More)
To evaluate gastrointestinal motility during 5-fluorouracil (5-FU)-induced intestinal mucositis. Wistar rats received 5-FU (150 mg kg−1, i.p.) or saline. After the 1st, 3rd, 5th, 15th and 30th day,(More)
CONTEXT Methotrexate and other anticancer agents can induce intestinal mucositis, which is one of the most common limiting factor that prevent further dose escalation of the methotrexate. (More)