José María Menéndez

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This paper deals with the problem of observability of traffic networks, understanding as such the problem of identifying which is the subset of the origin-destination (OD)-pair and link flows that can be calculated based on a subset of observed OD-pair and link flows, and related problems. A modified topological version of an existing algebraic method for(More)
BACKGROUND AND OBJECTIVES MicroRNAs (miRNAs) are small, noncoding RNAs that are involved in carcinogenesis through postranscriptional gene regulatory activity. Few studies have focused on the detection of miR-21 in serum rather than in tissue. The current study aimed to measure serum miR-21 expression levels and to evaluate their association with the(More)
MicroRNAs are short non-coding RNA molecules involved in the regulation of gene expression. There are few studies related to the determination of serum microRNAs in colorectal cancer. The identification of microRNAs in peripheral blood as noninvasive markers of tumor disease may lead to potential applications, although further clinical studies focusing on(More)
A stochastic demand dynamic traffic model is presented to predict some traffic variables, such as link travel times, link flows, or link densities, and their time evolution in real networks. The model considers that the variables are generalized beta variables such that when they are marginally transformed to standard normal, they become multivariate(More)
RATIONALE AND OBJECTIVES The authors determine the relative effect of soft-tissue compartments, body fat (percent [%Bfat] and weight [Bfat kg]) and fat-free mass (FFM kg), on measurements of ultrasound bone velocity (UBV m/second). METHODS The authors measured UBV in proximal phalanxes and body fat and fat-free mass by near infrared interactance in 40(More)
MicroRNAs are short non-coding RNA molecules that participate in the regulation of gene expression. Several studies have demonstrated the involvement of microRNAs in oncogenesis and a variety of physiological functions. We conducted a literature review of studies that evaluated histological microRNAs in colorectal cancer. Although additional clinical(More)