José-Manuel Olivares

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A double-blind clinical trial of clomipramine versus phenelzine was carried out on 30 patients suffering from DSM-III obsessive-compulsive disorder. The study period was 12 weeks, and the maximum doses used (from the fifth week on) were 225 mg/day for clomipramine (14 patients) and 75 mg/day for phenelzine (12 patients); four patients dropped out. Obsessive(More)
OBJECTIVE To evaluate the safety and tolerability of olanzapine in the treatment of elderly patients with schizophrenia. METHODS A total of 135 outpatients with schizophrenia > or =60 years of age were treated with olanzapine (n = 105) or another antipsychotic (n = 30) and followed up for 6 months. Safety measures included the recording of spontaneous(More)
This report explores the role played by DSM-III Major Depression in the Nonsuppressor status of a sample of 29 subjects suffering from DSM-III Obsessive Compulsive Disorder (OCD). Five subjects were found to be Nonsuppressors. Further analysis showed that it is likely that Nonsuppressor status depended upon the concomitant presence of Major Depression(More)
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