José Manuel Fonseca

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Agents that buy and sell goods or services in an electronic market need to adapt to the environment's prevailing conditions if they are to be successful. Here we propose an on-line, continuous learning mechanism that is especially adapted for agents to learn how to behave when negotiating for resources (goods or services). Taking advantage of the specific(More)
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Managing resources in the framework of the civil construction sector is usually an extremely complex task. The great number as well as the variety of existing resources, both human and material, the diversity of tasks each working unity is able to execute, the degree of quality of its performance, the involved costs, the spatial distribution of all(More)
BACKGROUND Drusen are common features in the ageing macula associated with exudative Age-Related Macular Degeneration (ARMD). They are visible in retinal images and their quantitative analysis is important in the follow up of the ARMD. However, their evaluation is fastidious and difficult to reproduce when performed manually. METHODS This article proposes(More)
Negotiation is a kind of decision making where two or more parties jointly search a space of solutions with the goal of reaching a consensus. This search usually is a single dimension process where the different agents, involved in the negotiation process, mutually adapt their price offers in order to reach their goals (to sell or to buy a good). However,(More)
MOTIVATION Cell division in Escherichia coli is morphologically symmetric. However, as unwanted protein aggregates are segregated to the cell poles and, after divisions, accumulate at older poles, generate asymmetries in sister cells' vitality. Novel single-molecule detection techniques allow observing aging-related processes in vivo, over multiple(More)
The huge development of the information systems in the last decades has, in many aspects, not been followed by the medical industry mainly due to legal and ethical issues that influence this specific area. Information sharing is in fact difficult and often impossible when we deal with patients data. Therefore, the creation of large centralized databases(More)