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OBJECTIVE To study how functional connectivity of neonate EEG during sleep is assessed by different interdependence indices and to analyze its dependence on conceptional (CA), gestational (GA) and/or chronological age (CRA). METHODS EEG data from eight cortical regions were recorded during active (AS) and quiet sleep (QS) in three groups of seven neonates(More)
This work aims at assessing the maturational changes in the interdependence between the activities of different cortical areas in neonates during active sleep (AS) and quiet sleep (QS). Eight electroencephalography (EEG) channels were recorded in 3 groups of neonates of increasing postmenstrual age. The average linear (AVL) and average nonlinear (AVN)(More)
The topography of the EEG of human neonates is studied in terms of its power spectral density and its estimated complexity as a function of both the postmenstrual age (PMA) and the sleep state. The monopolar EEGs of three groups of seven neonates (preterm, term and older term) were recorded during active (AS) and quiet sleep (QS) from electrodes Fp1, Fp2,(More)
The multichannel electroencephalograph (EEG) of six healthy term neonates was recorded during awake as well as during active and quiet sleep. The existence and nature of the interdependencies among the different brain areas were studied by means of a multivariate variant of the surrogate data method. Such interdependencies were then quantified by using the(More)
This tutorial is based on the book with the same title, published by Springer, 2009. The tutorial presents an introduction to object oriented simulation modeling and using the OOSimL simulation language for implementing the simulation models. The emphasis is on early introduction to simulation because simulation is considered an important area in the(More)
Complex aneurysmal disease of the thoracic aorta is commonly treated with the elephant trunk technique using two-stage surgery. However, this procedure is associated with high morbidity and mortality. We present the surgical technique used to correct diffuse aneurysmal aortic disease that involves the aortic arch and the descending aorta. The frozen(More)
Because of the pleiotropic effects of statins, it may potentially be used as a locoregional adjuvant in vascular revascularization, tissue engineering, and regenerative procedures. Electron probe X-ray microanalyses and oligonucleotide microarrays were used to identify the global effects of micromolar concentrations of atorvastatin on the gene expression(More)
The value of modeling and simulation for education, training, and testing in information security has been documented in several studies. In this paper, we suggest that it is important not only to include the general use of simulation in various courses of the security curriculum, but also to include the theory and development of simulation models. We(More)
The role of the induction of oxidative stress as the mechanism of action of many antitumor drugs is acquiring an increasing interest. In such cases, the antitumor therapy success may be conditioned by the antioxidants present in our own body, which can be synthesized de novo (endogenous) or incorporated through the diet and nutritional supplements(More)