José M Beltrán de Heredia

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In this study, we report the case of a Philadelphia (Ph) positive chronic myelogenous leukemia (CML) patient with the presence of p190 and p210 BCR-ABL1 mRNA fusion transcripts derived from e1a2 and b3a2 BCR-ABL1 genomic rearrangements, respectively. The presence of e1a2 BCR-ABL1 genomic rearrangement was seen in 2 different clones, one with the(More)
Therapeutic results in elderly patients with acute promyelocytic leukemia (APL) have been generally reported as less effective than for younger patients. Patients 60 years or older with APL who were enrolled in 2 successive multicenter PETHEMA studies received induction therapy with all-trans retinoic acid (ATRA) and idarubicin, consolidation with 3(More)
INTRODUCTION Subgroups having dissimilar prognoses are being identified among cancer patients with infection. Previous studies have suggested that these differences may be related to the histologic diagnosis, but this issue has not as yet been demonstrated. METHODS We reviewed the medical records of all patients admitted with acute leukemia (AL) or(More)
A new technique is reported for treatment of massive rectal prolapse, combining: mobilization of the rectum, colorectal fixation to the promontory and sacrum, "hammock-like" peritoneal autosuspension and obliteration of Douglas's pouch. The technique was successfully performed in six cases, with a follow-up ranging from one to six years; anal continence was(More)