José Luis Neyro

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BACKGROUND Letrozole is the third-generation aromatase inhibitor (AI) most widely used in assisted reproduction. AIs induce ovulation by inhibiting estrogen production; the consequent hypoestrogenic state increases GnRH release and pituitary follicle-stimulating hormone (FSH) synthesis. METHODS A systematic search of the literature was performed for both(More)
OBJECTIVE To compare the prevalence of endometriosis and its different stages in infertile women and women not exposed to spermatozoa. DESIGN Prospective study. SETTING Artificial insemination donor program at a university hospital. PATIENT(S) One hundred fifty women unable to conceive because they had not been exposed to spermatozoa (134 with(More)
OBJECTIVE The aim of this study was to assess the factors associated with the effectiveness of treatment with alendronate (ALN) quantified by a reduction in urinary excretion of N-telopeptide (NTx). METHODS The study is an observational, prospective, multicenter trial, with a 6-month follow-up. Postmenopausal osteoporotic women (densitometric criteria),(More)
Twenty-nine infertile women with polycystic ovary disease which was resistant to therapy with clomiphene citrate underwent a combined treatment for follicle recruitment consisting of pure FSH during the first days of the cycle and HMG during the last days of the follicular phase. Sixty cycles were stimulated of which 83% were ovulatory. Eighteen pregnancies(More)
OBJECTIVE To assess the relationship in infertile women between endometriosis and luteal phase defects and other infertility conditions. SETTING University Medical School. DESIGN Case-control study. PATIENTS One hundred and seventy-four infertile women with endometriosis and 174 infertile women without endometriosis, all of them studied by(More)
OBJECTIVES To determine women's perception of soy extracts containing a probiotic on climacteric-related symptoms. DESIGN A prospective multi-center survey. SUBJECTS AND METHODS A total of 2044 women aged 40-65 years, who were recruited at random by a group of 198 Spanish gynecologists. The women completed a self-report survey at baseline and after 6(More)
OBJECTIVE Fractures associated with bone fragility represent a major public health concern. Although the risk of bone fracture is higher among patients with osteoporosis, the number of fractures is usually higher among patients with osteopenia due to its higher prevalence. METHODS This is an observational case series study that compares the frequencies of(More)
The treatment course of a 29-year-old infertile woman using hMG and TDI was the cause of a sextuplet pregnancy in which a successful embryo reduction was carried out during the first trimester. The reduction was performed twice: the first around the 9th week of pregnancy transvaginally, and the second during the 12th week by transabdominal puncture. The(More)
Nine phenotypic female patients with XY karyotype were evaluated through a clinical, cytogenetic, hormonal, endoscopic and histologic diagnostic protocol. Seven patients complained of primary amenorrhea and two patients of abnormal puberal development. The final diagnosis was XY gonadal dysgenesis (n = 5) and testicular feminization syndrome (n = 4). Two(More)
BACKGROUND Osteoporosis is responsible for fragility fractures, which are associated with decreased physical and social function. The GINERISK study was a cross-sectional epidemiological study conducted in 4157 Spanish postmenopausal women initially diagnosed with osteoporosis according to WHO criteria within the last 2 years. AIM The aim of the study was(More)