José Luis Martínez González

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Neuron-derived orphan receptor-1 (NOR-1) plays a major role in vascular biology by controlling fibroproliferative and inflammatory responses. Because microRNAs (miRNAs) have recently emerged as key players in the regulation of gene expression in the vasculature, here we have investigated the regulation of NOR-1 by miRNAs in endothelial cells. Computational(More)
INTRODUCTION Fibulin-5 (FBLN5) is an elastogenic protein critically involved in extracellular matrix (ECM) remodelling, a key process in abdominal aortic aneurysm (AAA). However, the possible contribution of FBLN5 to AAA development has not been addressed. METHODS Expression levels were determined by real-time PCR and Western blot in human abdominal aorta(More)
OBJECTIVES To estimate the prevalence of drugs that interact with oral anticoagulants and establish relationships between variables and haemorrhagic complications. DESIGN Longitudinal, retrospective study of patient anticoagulant. SETTING Colmenar basic health area, Malaga, Spain. PARTICIPANTS Patients on anticoagulants followed up in primary care. (More)