José Luis Lerma

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BACKGROUND The experimental nephrosis induced in rats by adriamycin (ADR) or puromycin aminonucleoside (PA) provide a useful model to study the participation of inflammatory mediators in the pathogenesis of proteinuria. EXPERIMENTAL DESIGN We have measured tumor necrosis factor (TNF) and platelet-activating factor (PAF) production by glomeruli of rats(More)
We have studied the effect of therapy with plasma FN on glomerular synthesis of PAF, TNF-alpha and FN, in experimental proliferative glomerulonephritis. Glomerular PAF, TNF-alpha and FN production were increased in rats with nephritis. Peak glomerular PAF production preceded, while peak glomerular TNF-alpha bioactivity coincided with maximal proteinuria.(More)
Close-range photogrammetry is based on the acquisition of imagery to make accurate measurements and, eventually, three-dimensional (3D) photo-realistic models. These models are a photogrammetric product per se. They are usually integrated into virtual reality scenarios where additional data such as sound, text or video can be introduced, leading to(More)
Platelet-activating factor (PAF) is a potent autacoid that participates in inflammation and other pathophysiological processes. In this review we deal with recent evidence suggesting that PAF is a mediator that is released early during glomerular injury. PAF can be synthesized in the glomerulus by infiltrating intrinsic glomerular cells. Normal glomeruli(More)
The development of this article follows the search for a technique that automates the modelling and dynamics of any natural (dunes, slipping of mountainsides, glaciers…) or artificial (collapsing of buildings…) structure. In this study, the dynamics of the Argualas rock glacier (Pyrenees-Spain) has been investigated since 1991. A peculiarity of rocks(More)
The point density is a preeminent parameter on airborne laser scanner surveys. It is not only related to accuracy but costs and savings. The lack of uniformity of the point density across the survey is well-known in the scientific community. This paper analyzes the behaviour of the point density derived by an oscillating mirror laser scanner on different(More)