José Luis Ambite

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The Web of Linked Data is characterized by linking structured data from different sources using equivalence statements, such as owl:sameAs, as well as other types of linked properties. The ontologies behind these sources, however, remain unlinked. This paper describes an extensional approach to generate alignments between these ontologies. Specifically our(More)
The Web is based on a browsing paradigm that makes it difficult to retrieve and integrate data from multiple sites. y-k&y, the only w&y t;g & this is to bl_?ild_ specialized applications, which are time-consuming to develop and difficult to maintain. We are addressing this problem by creating the technology and tools for rapidly constructing information(More)
TRIPLE was designed as a practical rule language for data manipulation applications. Over the last couple of years the language has been deployed in various applications and use case studies. In this paper we first introduce the design principles of TRIPLE and then present some of the applications for which this language has been used.
For the past five years, genome-wide association studies (GWAS) have identified hundreds of common variants associated with human diseases and traits, including high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) levels. Approximately 95 loci associated with lipid levels have been identified(More)
The Web is based on a browsing paradigm that makes it diÆcult to retrieve and integrate data from multiple sites. Today, the only way to do this is to build specialized applications, which are time-consuming to develop and diÆcult to maintain. We have addressed this problem by creating the technology and tools for rapidly constructing information agents(More)
The Internet provides access to a wealth of information. For any given topic or application domain there are a variety of available information sources. However, current systems, such as search engines or topic directories in the World Wide Web, offer only very limited capabilities for locating, combining, and organizing information. Mediators, systems that(More)
The field of phenomics has been investigating network structure among large arrays of phenotypes, and genome-wide association studies (GWAS) have been used to investigate the relationship between genetic variation and single diseases/outcomes. A novel approach has emerged combining both the exploration of phenotypic structure and genotypic variation, known(More)
The power of web services can only be realized when web services are utilized as building blocks to dynamically compose new web services. The Building Finder application is an example application that integrates information from several web services by modeling the web services as information sources in a mediator-based architecture. The paper also(More)
Domain-independent planning is a hard combinatorial problem. Taking into account plan quality makes the task even more di cult. We introduce a new paradigm for e cient high-quality planning that exploits plan rewriting rules and e cient local search techniques to transform an easy-to-generate, but possibly suboptimal, initial plan into a low-cost plan. In(More)
Building Finder uses semantic Web technologies to integrate different data types from various online data sources. The application's use of the RDF and RDF data query language makes it usable by computer agents as well as human users. An agent would send a query, expressed in terms of its preferred ontology (schema), to a system that would then find and(More)