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Twenty-seven children and adolescents aged 4 to 18 years, fulfilling the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) criteria for attention-deficit hyperactivity disorder, were included in this study. The diagnosis was determined by a pediatric neurologist and a psychologist examined all 27 subjects with tests that included(More)
Different pesticides, including organophosphates (OPs), have been reported to induce oxidative stress due to generation of free radicals and alteration in antioxidant defence mechanisms. In this study, a cohort of 81 intensive agriculture workers (pesticide sprayers) was assessed twice during the course of a spraying season for changes in erythrocyte(More)
We report a new family of multifunctional liquid-crystalline porphyrin-core dendrimers that have coumarin functional groups around the porphyrin core. Porphyrin metalation strongly affects the photophysical properties, and therefore ZnII and CuII derivatives have also been prepared. All the synthesized dendrimers form a nematic discotic mesophase. Their(More)
From the point of view of the human disease, dogs are the most important animal reservoir of Lyme borreliosis; therefore, they are used as 'sentinel animals'. In order to know the epidemiological characteristics of dogs with antibodies against Borrelia burgdorferi, 146 canine sera samples collected during 1993-94 have been studied. The antibody detection(More)
In this tutorial review we describe some studies concerning liquid crystal dendritic polymers. We have chosen to present several representative examples that illustrate the diverse kinds of LC dendritic structures, namely: dendrimers, dendrons, dendronized polymers and hyperbranched polymers. We review their synthesis, mesogenic properties and the way that(More)
Changes in erythrocyte delta-aminolevulinic acid dehydratase (ALA-D) have been reported after exposure to different pesticides, including organophosphates and paraquat. In this study, we have determined ALA-D in 135 pesticide applicators (sprayers) from an intensive agriculture setting at two periods with different pesticide exposure. Acetylcholinesterase(More)
INTRODUCTION Nanostructured lyotropic liquid crystal particles (LLC NPs) have proven to be extremely useful tools for applications in drug delivery. These structured nanoparticles are formed by amphiphilic molecules and contain internal water channels, which are not in contact with external water, and where polar drugs can situate; on the other hand, apolar(More)
A synthetic strategy has been developed to prepare cyclotriphosphazenes that bear polycatenar aromatic esters as promesogenic units linked to phosphorus atoms. The microsegregation of the rigid and flexible parts of the system and the space-filling properties are the driving forces that determine the kind of mesomorphism exhibited by the(More)
New liquid crystals having a non-conventional structure have been synthesised from a six-armed cyclotriphosphazene core, [N(3) P(3) (OC(6) H(4) OH-4)(6) ], which was condensed with polycatenar acids. Reactions were monitored by (31) P{(1) H} and (1) H NMR spectroscopy and the chemical structure of the resulting materials was confirmed by different(More)
The self-assembly behaviour both in the bulk and water of a series of amphiphilic dendrimers constituted by second generation PAMAM ionically functionalized with different amounts of myristic acid is shown here. The number of acids in the dendrimer determines the liquid-crystal properties and the structural parameters of their supramolecular organization.(More)