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  • Marcella Nouzova, Nicholas Holtan, +7 authors Bernard W. Futscher
  • Biology, Medicine
  • The Journal of pharmacology and experimental…
  • 2004 (First Published: 1 December 2004)
  • Dysregulation of epigenetic control is an important participant in carcinogenesis. The PML/RAR alpha translocation in acute promyelocytic leukemia (APL) is an example where the resultant fusionContinue Reading
  • Shuxi Qiao, Sarah D. Lamore, Christopher M. Cabello, Jessica L. Lesson, José L. Muñoz-Rodríguez, Georg T Wondrak
  • Chemistry, Medicine
  • Biochemical pharmacology
  • 2012 (First Published: 1 May 2012)
  • Pharmacological induction of oxidative and proteotoxic stress has recently emerged as a promising strategy for chemotherapeutic intervention targeting cancer cells. Guided by a differentialContinue Reading
  • Xiangxue Wang, Shizen Moh, +9 authors Wenjun Zhang
  • Medicine
  • 2019 (First Published: 1 July 2019)
  • Introduction: Anti-PD-1/L1 immune checkpoint blockade results in tumor stabilization or shrinkage in only 15-40% of patients. Predictive biomarkers are crucial in identifying responsive patientsContinue Reading