José L. Perez-Escobedo

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This paper presents a discrete-event simulation environment that models the underlying structure of a pharmaceutical enterprise portfolio. An object-oriented model structure previously developed for batch plant scheduling and design is extended to embed the case of product management, which is particularly adequate for re-use of both structure and logic. By(More)
A fundamental challenge in managing a pharmaceutical company is identifying the optimal allocation of finite resources across the infinite constellation of available investment opportunities. In that context, the optimal management of the new product pipeline has emerged at the forefront of all strategic planning initiatives of a company. The combined use(More)
New Product Development (NPD) constitutes a challenging problem in the pharmaceutical industry, due to the characteristics of the development pipeline. Formally, the NPD problem can be stated as follows: select a set of R&D projects from a pool of candidate projects in order to satisfy several criteria (economic profitability, time to market) while coping(More)
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