1Maria Segura
1Sharron Vass
1Adriana Sampaio
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BACKGROUND The coordination of cell cycle events is necessary to ensure the proper duplication and dissemination of the genome. In this study, we examine the consequences of depleting Drad21 and SA, two non-SMC subunits of the cohesin complex, by dsRNA-mediated interference in Drosophila cultured cells. RESULTS We have shown that a bona fide cohesin(More)
  • Jaume Lucena, Susana Pezzi, Ester Aso, Maria C Valero, Candelas Carreiro, Pierre Dubus +9 others
  • 2010
BACKGROUND GTF2I codes for a general intrinsic transcription factor and calcium channel regulator TFII-I, with high and ubiquitous expression, and a strong candidate for involvement in the morphological and neuro-developmental anomalies of the Williams-Beuren syndrome (WBS). WBS is a genetic disorder due to a recurring deletion of about 1,55-1,83 Mb(More)
  • Ana M Valdeolmillos, Alberto Viera, Jesús Page, Ignacio Prieto, Juan L Santos, María Teresa Parra +5 others
  • 2007
The cohesin complexes play a key role in chromosome segregation during both mitosis and meiosis. They establish sister chromatid cohesion between duplicating DNA molecules during S-phase, but they also have an important role during postreplicative double-strand break repair in mitosis, as well as during recombination between homologous chromosomes in(More)
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