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  • José João Mansure, Roland Nassim, Simone Chevalier, Joice Rocha, Eleonora Scarlata, Wassim Kassouf
  • Biology, Medicine
  • Cancer biology & therapy
  • 2009 (First Published: 15 December 2009)
  • We examined whether mTOR inhibition by RAD001 (Everolimus) could be therapeutically efficacious in the treatment of bladder cancer. RAD001 markedly inhibited proliferation of nine human urothelialContinue Reading
  • Roland Nassim, José João Mansure, Simone Chevalier, Fábio Cury, Wassim Kassouf
  • Chemistry, Medicine
  • PloS one
  • 2013 (First Published: 17 June 2013)
  • PURPOSE Radiation therapy for invasive bladder cancer allows for organ preservation but toxicity and local control remain problematic. As such, improving efficacy of treatment requiresContinue Reading
  • Bin Xu, Samuel Abourbih, +5 authors Fadi Brimo
  • Biology, Medicine
  • Archives of pathology & laboratory medicine
  • 2013 (First Published: 1 October 2013)
  • CONTEXT Enhancer of zeste homolog 2 (EZH2), a histone methyltransferase mediating chromatin condensation and epigenetic modulation, is overexpressed in various human carcinomas and is associated withContinue Reading