José Ignacio Botella Carretero

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BACKGROUND Our purpose was to establish the efficacy of different diagnostic tests for the diagnosis and localization of insulinoma as well as the prognostic value of postoperative glycemia measurements. PATIENTS AND METHOD Retrospective analysis of all insulinoma patients diagnosed at our hospital over the last fifteen years. Every patient underwent a(More)
BACKGROUND AND AIM In recent years, smoking has been shown to increase insulin resistance. However, other studies have failed to demonstrate this association after correcting for confounding factors such as age, gender, body mass index (BMI) or waist to hip ratio (WHR). This study was conducted to elucidate the relative contributions of smoking, obesity and(More)
BACKGROUND Sexual dimorphism manifests noticeably in obesity-associated gonadal dysfunction. In women, obesity is associated with androgen excess disorders, mostly the polycystic ovary syndrome (PCOS), whereas androgen deficiency is frequently present in obese men in what has been termed as male obesity-associated secondary hypogonadism (MOSH).(More)
Distant metastases are a rare occurrence in differentiated thyroid cancer, and when detected in skin, often arise in the context of disseminated disease after many years of progression since diagnosis. This study presents the case of a 77-year-old female without known thyroid disease, who presented with metastases in the parieto-occipital scalp region, in(More)
BACKGROUND AND AIMS It has been recently shown that psychiatric disorders are associated with obesity. However this association has not been studied in overweight/obese patients at a hospital setting in our country. PATIENTS AND METHODS We have studied 333 consecutive patients who were referred to our hospital outpatient clinic with overweight or obesity.(More)
Leptin is a protein that has been identified three years ago, but its role, or at least its deficiency, was suspected from 1950. Dickie and coworkers reported the appearance of a mutant rat in one of their colonies with morbid obesity. The genetic defect was autosomal recessive and was manifested early in life. In December 1994, the gen ob was cloned, which(More)
The metabolic syndrome, defined as the association of abdominal obesity, insulin resistance, dyslipidemia and hypertension, is a very prevalent disorder. Moreover, it identifies patients with a high cardiovascular risk, and when diagnosed, life style modifications and/or drug therapy can be initiated in these patients with the aim to reduce their(More)
We present a case of severe chronic diarrhea requiring parenteral nutritional support to both cover the nutritional needs and allow for intestinal rest for later adaptation to enteral nutrition, altogether allowing for the etiologic diagnosis and disease healing.
The authors presented their information in a poster format at the VI GAVeCeLT National Congress "VI Congresso Nazionale GAVeCeLT (Centro Congressi Europa, Università Cattolica del Sacro Cuore)". The authors point out that the use of less invasive systems, such as a PICC catheter (peripherally inserted central catheter), produce excellent results, provided(More)