José García Feyling

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CONTEXT Aromatase is the key enzyme for estrogen biosynthesis and is encoded by the CYP19A1 gene. Since 1991, several molecular CYP19A1 gene alterations associated with aromatase deficiency have been described in both sexes. OBJECTIVE The objective of the study was to detect CYP19A1 mutations in five aromatase-deficient 46,XX patients, to describe the(More)
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