José F R Ornellas

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To understand the mechanisms responsible for the persistent hypercalciuria and reduced glomerular filtration rate (GFR) previously found in 6 of 10 patients surgically cured of primary hyperparathyroidism (PHPx), the tubular handling of lithium, sodium, calcium, and phosphate as well as the renal hemodynamics were evaluated in these 10 PHPx patients, in 10(More)
BACKGROUND/AIMS Unilateral ureteral obstruction (UUO) in rats has been used as a model of renal interstitial fibrosis, in which therapeutic trials can be of important clinical relevance. In this study, we investigated the effects of mycophenolate mofetil (MMF), the angiotensin-converting enzyme (ACE) inhibitor lisinopril (L), and the combination of both(More)
1. There is clinical and experimental evidence that females are more susceptible to gentamicin-induced nephrotoxicity. To assess the role of sex as a risk factor in aminoglycoside-related acute renal failure 16 groups of five 120 +/- 15-day old (young adult) Wistar rats of both sexes, castrated and non-castrated, were treated with gentamicin. These rats(More)
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