José David Martín-Guerrero

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In this paper, we propose the use of Support Vector Machines (SVM) for automatic hyperspectral data classification and knowledge discovery. In the first stage of the study, we use SVMs for crop classification and analyze their performance in terms of efficiency and robustness, as compared to extensively used neural and fuzzy methods. Efficiency is assessed(More)
The theory of extreme learning machine (ELM) has become very popular on the last few years. ELM is a new approach for learning the parameters of the hidden layers of a multilayer neural network (as the multilayer perceptron or the radial basis function neural network). Its main advantage is the lower computational cost, which is especially relevant when(More)
Feature Selection (FS) is one of the key stages in classification problems. This paper proposes the use of the area under Receiver Operator Characteristic curves to measure the individual importance of every input as well as a method to discover the variables that yield a statistically significant improvement in the discrimination power of the(More)
This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises 315 AO molecules including 68 features each, inducing a problem well-suited to SVMs. The task of feature selection is crucial given the presence of noisy or redundant features, and the(More)
This article is not intended as a comprehensive survey of data mining applications in cancer. Rather, it provides starting points for further, more targeted, literature searches, by embarking on a guided tour of computational intelligence applications in cancer medicine, structured in increasing order of the physical scales of biological processes.
The commodification of healthcare has led to an increasing demand for personalization of patients’ treatments. Meeting this demand requires not only the commitment of abundant resources, but also a sophisticated management of information systems, leading to initiatives such as the standardization of electronic health records. As these become mainstream, the(More)
This paper proposes the use of neural networks for individualizing the dosage of cyclosporine A (CyA) in patients who have undergone kidney transplantation. Since the dosing of CyA usually requires intensive therapeutic drug monitoring, the accurate prediction of CyA blood concentrations would decrease the monitoring frequency and, thus, improve clinical(More)
This paper presents a methodology to estimate the future success of a collaborative recommender in a citizen web portal. This methodology consists of four stages, three of them are developed in this study. First of all, a user model, which takes into account some usual characteristics of web data, is developed to produce artificial data sets. These data(More)