José Carlos Pastor Pareja

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OBJECTIVE Inflammation and dysfunction of the hypothalamus are common features of experimental obesity. However, it is unknown whether obesity and massive loss of body mass can modify the immunologic status or the functional activity of the human brain. Therefore, the aim of this study was to determine the effect of body mass reduction on brain(More)
BACKGROUND The major adverse consequences of obesity are associated with the development of insulin resistance (IR) and adiposopathy. The Homeostasis Model Assessment-Adiponectin (HOMA-AD) was proposed as a modified version of the HOMA1-IR, which incorporates adiponectin in the denominator of the index. OBJECTIVES To evaluate the performance of the(More)
BACKGROUND Sagittal abdominal diameter (SAD) has been proposed as a surrogate marker of insulin resistance (IR). However, the utilization of SAD requires specific validation for each ethnicity. We aimed to investigate the potential use of SAD, compared with classical anthropometrical parameters, as a surrogate marker of IR and to establish the cutoff values(More)
OBJECTIVEdTo investigate the effect of biliopancreatic diversion (BPD) surgery on b-cell function in grade I and II obese patients with type 2 diabetes using oral and intravenous glucose loads. RESEARCH DESIGN AND METHODSdSixty-eight women were divided into the following three groups: 19 lean-control (23.0 6 2.2 kg/m 2) and 18 obese-control (35.0 6 4.8 kg/m(More)
A.1 Análisis Genético de mecanismos morfogenéticos en Drosophila A.2 Mecanismos de señalización en el desarrollo A.3 Biología molecular del desarrollo de Drosophila A.4 Control genético de la morfogénesis A.5 Comunicación intercelular en el desarrollo de drosophila A.6 Control genético de la división celular en drosophila A.1 Genetic Analysis of(More)
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