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BACKGROUND Colorectal tumors caused by failure of the DNA mismatch repair system commonly show microsatellite instability. Our goals were to compare the performance of two panels of markers (a panel previously recommended by the National Cancer Institute [NCI] and a pentaplex of mononucleotide repeats) and to devise the simplest diagnostic strategy for(More)
OBJECTIVE The use of colonoscopy as a primary screening test for colorectal cancer (CRC) in average risk adults is a subject of controversy. Our primary objective was to build a predictive model based on a few simple variables that could be used as a guide for identifying average risk adults more suitable for examination with colonoscopy as a primary(More)
PURPOSE Previous publications have linked Herbalife® products to hepatotoxicity. The identification of earlier cases in which the culprit agent could not be established raised the hypothesis of a possible contamination of some specific batches of Herbalife products. METHODS We searched the Spanish Pharmacovigilance Centres' database of adverse reactions(More)
BACKGROUND For colorectal cancer screening, the predictive value of distal findings in the ascertainment of proximal lesions is not fully established. The aims of this study were to assess distal findings as predictors of advanced proximal neoplasia and to compare the predictive value of endoscopy alone vs. combined endoscopic and histopathologic data. (More)
In this work, we study the convergence of the finite element method when applied to the following parabolic equation: u t = div(|u| γ(x) ∇u) + λ|u| σ(x,t)−2 u + f (x, t), x ∈ Ω ⊂ R d , t ∈]0, T ]. Since the equation may be of degenerate type, we utilize an approximate problem , regularized by introducing a parameter ε. We prove, under certain conditions on(More)