José C. Calvo

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Protein structure prediction (PSP) is an open problem with many useful applications in disciplines such as medicine, biology and biochemistry. As this problem presents a vast search space and the analysis of each protein structure requires a significant amount of computing time, it is necessary to take advantage of high-performance parallel computing(More)
Affymetrix High Oligonucleotide expression arrays, also known as Affymetrix GeneChips, are widely used for the high-throughput assessment of gene expression of thousands of genes simultaneously. Although disputed by several authors, there are non-biological variations and systematic biases that must be removed as much as possible before an absolute(More)
The protein structure prediction (PSP) problem is considered an open problem as there is no recognized " best " procedure to find solutions. Moreover, this problem presents a vast search space and the analysis of each protein conformation requires significant amount of computing time. We propose a reduction of the search space by using the dependent rotamer(More)
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