José Augusto Nogueira-Machado

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BACKGROUND The present study was designed to investigate the hypothesis that cells from ill patients and from healthy subjects may have different reactivities under metabolic stimulation. METHODS(More)
Toll-like receptors (TLRs) play an important role in several inflammatory diseases such as diabetes. The present study was to determine whether hyperglycemia in diabetes interferes in reactive oxygen(More)
The respiratory burst reaction has been studied in human granulocytes from normal subjects divided in four age groups: (I) 20-29, (II) 30-39, (III) 40-49, and (IV) 50-59 years old. Zimosan opsonized(More)
We examined nitric oxide (NO), IL-6, and TNF-α secretion from cultured palmitate-stimulated PBMNCs or in the plasma from type 2 diabetes mellitus (T2MD) patients or nondiabetic (ND) controls. Free(More)
In this present paper the age-induced effect on reactive oxidizing species generated by oxygen (ROS) and nitrogen (RNS) was studied using human phagocyting granulocytes. The ROS and RNS were(More)