José Arturo Prada-Oliveira

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Goto-Kakizaki rats are an important model of type 2 diabetes, but it is difficult to maintain and expand colonies of these rats because they exhibit poor fertility. In this work, we studied the estrous cycle of Goto-Kakizaki and Wistar rats to characterize differences that might underlie these reproductive difficulties. We monitored rats from weaning to(More)
Several surgical techniques are used nowadays as a severe treatment for obesity and diabetes mellitus type 2. These techniques are aggressive due to drastic changes in the nutrient flow and non-reversible modifications on the digestive tube. In this paper we present the effects of a massive intestinal resection on the pancreas. Results have shown that short(More)
BACKGROUND The aim of this study was to investigate the relation between the different bariatric surgeries and pancreatic β-cell turnover. MATERIAL AND METHODS We used healthy adult male Wistar rats to undergo the different techniques. Three surgical techniques were developed (malabsorptive, Sleeve gastrectomy and Roux-Y Gastric Bypass-), together with(More)
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