José Arturo Prada-Oliveira

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Goto-Kakizaki rats are an important model of type 2 diabetes, but it is difficult to maintain and expand colonies of these rats because they exhibit poor fertility. In this work, we studied the estrous cycle of Goto-Kakizaki and Wistar rats to characterize differences that might underlie these reproductive difficulties. We monitored rats from weaning to(More)
BACKGROUND The aim of this study was to investigate the relation between the different bariatric surgeries and pancreatic β-cell turnover. MATERIAL AND METHODS We used healthy adult male Wistar rats to undergo the different techniques. Three surgical techniques were developed (malabsorptive, Sleeve gastrectomy and Roux-Y Gastric Bypass-), together with(More)
Several surgical techniques are used nowadays as a severe treatment for obesity and diabetes mellitus type 2. These techniques are aggressive due to drastic changes in the nutrient flow and non-reversible modifications on the digestive tube. In this paper we present the effects of a massive intestinal resection on the pancreas. Results have shown that short(More)
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