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Virtual machines provide flexible, powerful execution environments for Grid computing, offering isolation and security mechanisms complementary to operating systems, customization and encapsulation of entire application environments, and support for legacy applications. This paper describes a Grid service ¿ VMPlant ¿ that provides for automated… (More)
This paper describes the architecture of the first implementation of the In-VIGO grid-computing system. The architecture is designed to support computational tools for engineering and science research In Virtual Information Grid Organizations (as opposed to in vivo or in vitro experimental research). A novel aspect of In-VIGO is the extensive use of… (More)
One of the most important goals of data-center management is to reduce cost through efficient use of resources. Virtualization techniques provide the opportunity of carving individual physical servers into multiple virtual containers that can be run and managed separately. A key challenge that comes with virtualization is the simultaneous on-demand… (More)
—This paper proposes and evaluates an approach to the parallelization, deployment and management of bioinformatics applications that integrates several emerging technologies for distributed computing. The proposed approach uses the MapReduce paradigm to parallelize tools and manage their execution, machine virtualization to encapsulate their execution… (More)
This paper addresses the architectural issues that arise in the design of a universally accessible wide-area network-computing system that is capable of making automatic cost/performance tradeoo decisions at run-time. The core system is designed around a three-level hierarchically distributed architecture, a choice driven by the dynamic, incremental, and… (More)