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Infrastructure-as-a-service (IaaS) cloud computing is revolutionizing how we approach computing. Compute resource consumers can eliminate the expense inherent in acquiring, managing, and operating IT infrastructure and instead lease resources on a pay-as-you-go basis. IT infrastructure providers can exploit economies of scale to mitigate the cost of buying(More)
Server consolidation using virtualization technology has become increasingly important for improving data center efficiency. It enables one physical server to host multiple independent virtual machines (VMs), and the transparent movement of workloads from one server to another. Fine-grained virtual machine resource allocation and reallocation are possible(More)
—This paper proposes and evaluates an approach to the parallelization, deployment and management of bioinformatics applications that integrates several emerging technologies for distributed computing. The proposed approach uses the MapReduce paradigm to parallelize tools and manage their execution, machine virtualization to encapsulate their execution(More)
Virtual machines provide flexible, powerful execution environments for Grid computing, offering isolation and security mechanisms complementary to operating systems, customization and encapsulation of entire application environments, and support for legacy applications. This paper describes a Grid service ¿ VMPlant ¿ that provides for automated(More)
One of the most important goals of data-center management is to reduce cost through efficient use of resources. Virtualization techniques provide the opportunity of carving individual physical servers into multiple virtual containers that can be run and managed separately. A key challenge that comes with virtualization is the simultaneous on-demand(More)
Most data centers, clouds and grids consist of multiple generations of computing systems, each with different performance profiles, posing a challenge to job schedulers in achieving the best usage of the infrastructure. A useful piece of information for scheduling jobs, typically not available, is the extent to which applications will use available(More)
The trend towards multi-/many- core design has made network-on-chip (NoC) a crucial component of future microprocessors. With CMOS processing technologies continuously scaling down to the nanometer regime, effects such as process variation (PV) and negative bias temperature instability (NBTI) significantly decrease hardware reliability and lifetime.(More)