Joris van den Heuvel

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Increased physical activity and decreased motivation to eat are common features in anorexia nervosa. We investigated the development of these features and the potential implication of brain-derived neurotrophic factor (BDNF) and dopaminergic signalling in their development in C57BL/6J and A/J inbred mice, using the 'activity-based anorexia' model. In this(More)
We investigated if nonnutritive sucking (NNS) during heelstick procedures alleviates behavioral distress in neonates. In our NICU, 26 neonates without severe complications (mean Minde score 0.8, range 0-3), undergoing heelstick procedures at least twice a day, in the first 2 weeks of life, were enrolled in the trial (mean gestational age 33.9 weeks, range(More)
OBJECTIVE The objective was to examine the added diagnostic value of on-site urine toxicology screening (UTS) in the routine assessment of psychiatric patients in an urban emergency setting. METHOD A naturalistic two-step prospective cohort study design was used enrolling all emergency room (ER) patients referred for psychiatric consultation. In two(More)
In cooperation with the Rotterdam School of Management of the Erasmus University in Rotterdam, an expert system GUUS was developed in the intensive care unit of the Department of Thoracic Surgery of the Leiden University Hospital. This expert system is able to diagnose postoperative haemodynamic problems in patients after coronary artery surgery and can(More)