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Light and electron microscopy were used to investigate the morphology of neuropil and neuronal cell bodies of the dorsal lateral geniculate nucleus (LGNd) of aged rats. Light microscopic examination reveals that, despite the optic tract showing signs of degeneration, the LGNd is scarcely affected. Thus, a slight but significant reduction in the diameters of(More)
The variations, with aging, of both neuronal and glial populations of the rat LGNd have been studied quantitatively. Our results show a stability of the total number of neurons of the rat LGNd with aging; this, plus the constant increase of the rat LGNd volume throughout rat life, causes the neuronal density to decrease slowly. Our data prove the necessity(More)
Hereditary bilateral macular colobomata are not a consequence of an anomalous closure of the fetal fissure. Their extreme rarity, their lack of embryological explanation, and their morphologic similarity to postinflammatory congenital macular scars called the hereditary-malformative etiology of this entity in question. The authors describe a four generation(More)
The postnatal development of complex convolutions (CCs) of the dorsal lateral geniculate nucleus (LGNd) in normal rats has been studied quantitatively with light microscopy. We report that immature neurons do not contain these scarcely understood organelles, since they can be seen for the first time in very few, mature neurons of the 30 day rat; their(More)
Quantitative changes in cell number during development of the dorsal lateral geniculate nucleus were determined using semithin serial sections of tissue obtained from 28 rats on postnatal day 0, 5, 8, 10, 20, 30, 90 or 165. Our results show three phases of postnatal development in the rat dorsal lateral geniculate nucleus: phase 1 from birth until eye(More)
A reversed-phase ion-pair high-performance liquid chromatographic method has been used for the separation of paracetamol and its four major metabolites (glucuronide, sulphate, cysteine and mercapturate conjugates) in mouse plasma samples. An ODS column was used and the mobile phase consisted of an aqueous solution of 0.01 M tetrabutylammonium chloride and(More)
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