Jorge Sanchez-Salazar

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 We are characterizing members of the Transforming Growth Factor-β (TGF-β) superfamily in the red flour beetle, Tribolium castaneum, in order to examine the evolutionary conservation of the structure and function of TGF-β-like genes during insect development. A decapentaplegic-like gene of the TGF-β superfamily was isolated in Tribolium (Tc dpp) that is(More)
The most characteristic neuropathologic features of prion diseases are accumulation of PrPSc in the brain and vacuolation of neurons. Neuronal vacuolation suggests plasma membrane dysfunction. In an earlier study, we found that bradykinin (Bk)-stimulated Ca2+ responses in scrapie-infected ScN2a cells were reduced by 30 to 50% compared with uninfected N2a(More)
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