Jorge Mendoza

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Pre- and post-treatment measurements of C-reactive protein (CRP) in 85 patients with acute brucellosis were useful in predicting the disease's evolution and response to treatment. A positive value for CRP (greater than 1 microgram/dl) was significantly associated with an unfavorable course, with a negative predictive value of 0.95.
Exposure to light at night (LAN) is associated with insomnia in humans. Light provides the main input to the master clock in the hypothalamic suprachiasmatic nucleus (SCN) that coordinates the sleep-wake cycle. We aimed to develop a rodent model for the effects of LAN on sleep. Therefore, we exposed male Wistar rats to either a 12 h light (150-200lux):12 h(More)
AIM To assess the clinical, biochemical and virological long-term outcome in chronic hepatitis C (CHC) patients with a sustained virological response (SVR) after peginterferon (PEG-IFN) plus ribavirin combination therapy. METHODS One hundred and fifty three patients with a SVR after treatment with PEG-IFN plus ribavirin were included in a 5-year follow-up(More)
Determinants of safer sexual behaviors (abstinence or consistent condom use) among female partners of HIV-infected adult men with hemophilia were examined. A model was proposed predicting that emotional adjustment, communication skills, self-efficacy, and perceived advantages of condom use would influence the practice of safer sexual behaviors. Confidential(More)
BACKGROUND Methotrexate is useful in inflammatory bowel disease (IBD), but its role is secondary because of its limited experience and a supposedly unfavorable safety profile. AIM To describe the efficacy and safety of methotrexate in a long-term real clinical practice. METHODS Retrospectively reviewed records of IBD patients treated with methotrexate(More)
BACKGROUND AND AIMS Methotrexate (MTX) safety is questioned by the risk of inducing liver fibrosis (LF). As transient elastography (FibroScan®) is an effective non-invasive technique to evaluate LF, our aims were to assess LF in MTX-treated patients, to evaluate LF regarding treatment duration and cumulative dose, and to determine differences depending on(More)
We describe three cases of extragenital infection by Mycoplasma hominis in three patients transplanted with kidneys from cadaver donors. In two patients, the microorganism was isolated in the exudate from the surgical wound after 72 hrs. of culture on blood-agar (Columbia + 5% horse blood) in CO2 and under anaerobic conditions. In the remaining case, M.(More)
The kisspeptin (Kp) neurons in the anteroventral periventricular nucleus (AVPV) are essential for the preovulatory LH surge, which is gated by circulating estradiol (E2) and the time of day. We investigated whether AVPV Kp neurons in intact female mice may be the site in which both E2 and daily signals are integrated and whether these neurons may host a(More)