#### Filter Results:

- Full text PDF available (2)

#### Publication Year

2006

2016

- This year (0)
- Last 5 years (1)
- Last 10 years (5)

#### Publication Type

#### Co-author

#### Journals and Conferences

Learn More

- Ana Figueiras, J. M. G. Sarraguça, Rui A. Carvalho, A. A. C. C. Pais, Francisco J. B. Veiga
- Pharmaceutical Research
- 2006

Cyclodextrins are known to be good solubility enhancers for several drugs, improving bioavailability when incorporated in pharmaceutical formulations. In this work we intend to assess and characterize the formation of inclusion complexes between omeprazole (OME) and a methylated derivative of β-cyclodextrin, methyl-β-cyclodextrin (MβCD). A comparison with… (More)

- Ana Figueiras, Jorge M. G. Sarraguça, Alberto A. C. C. Pais, Rui A. Carvalho, J. Francisco Veiga
- AAPS PharmSciTech
- 2009

In this study, we investigate how the effect of l-arginine (ARG) and cyclodextrins upon omeprazole (OME) stability and solubility. The effect of the presence of ARG on the apparent stability constants (K1:1) of the inclusion complexes formed between OME and each cyclodextrin, β-cyclodextrin (βCD), and methyl-β-cyclodextrin (MβCD) is studied by phase… (More)

- J M G Sarraguça, R S Dias, A A C C Pais
- Journal of biological physics
- 2006

In this work we discuss different factors governing coil-globule coexistence in the compaction process of DNA. We initially analyse the role played by fluctuations in the degree of binding of an external compacting agent in the conformational behavior of the chain backbone. The analysis relies both on Monte Carlo simulation results and simple statistical… (More)

- J M G Sarraguça, A A C C Pais
- Physical chemistry chemical physics : PCCP
- 2006

It has been experimentally observed that trivalent ions are capable of promoting compaction of semi-flexible polyelectrolyte chains. In this work we perform Monte Carlo simulations on single chain model systems with varying chain size and stiffness and evaluate the action of multivalent salt on the chain conformation. It is observed that longer chains tend… (More)

- Jorge M G Sarraguça, Catarina Lima, +5 authors Agostinho Santos
- The Analyst
- 2016

A new methodology to estimate firing distance based on the direct analysis of organic components of gunshot residues (GSRs) on the bullet impact surface using Fourier transform near-infrared (FT-NIR) spectroscopy is proposed. Mathematical models relating firing distance with spectral information were developed using data obtained from a series of shots… (More)

- Marı́a José Tapia, Hugh D. Burrows, +4 authors J. M. G. Sarraguça
- 2009

The interaction of trivalent lanthanides with sodium dodecyl sulfate micelles (SDS) in aqueous solution has been studied by a variety of experimental techniques. Potentiometric measurements with a sodium selective electrode, steady-state fluorescence spectra of Ce(III), emission lifetime measurements of Ce(III), Tb(III), and Eu(III), and electronic… (More)

- J M G Sarraguça, A A C C Pais, Per Linse
- Langmuir : the ACS journal of surfaces and…
- 2008

Structural equilibrium properties of transient networks formed by microemulsion droplets and ABA triblock copolymers in solution have been studied by Monte Carlo simulation. The droplets were represented by soft spheres, and the polymers were represented by junctions connected by harmonic bonds with an angular potential regulating the intrinsic chain… (More)

- A F Jorge, J M G Sarraguça, R S Dias, A A C C Pais
- Physical chemistry chemical physics : PCCP
- 2009

Compaction of negatively charged polyanions by polycations with different characteristics is investigated using Monte Carlo simulation in a coarse-grain model. Two different routes are tested and the results compared. In one, the polycation/polyanion charge ratio is varied by increasing the amount of polycations, keeping all the chain characteristics… (More)

- ‹
- 1
- ›