Jorge Duarte

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Despite the complete determination of the genome sequence of several higher eukaryotes, their proteomes remain relatively poorly defined. Information about proteins identified by different experimental and computational methods is stored in different databases, meaning that no single resource offers full coverage of known and predicted proteins. IPI (the(More)
The 5' and 3' untranslated regions of eukaryotic mRNAs play crucial roles in the post-transcriptional regulation of gene expression through the modulation of nucleo-cytoplasmic mRNA transport, translation efficiency, subcellular localization and message stability. UTRdb is a curated database of 5' and 3' untranslated sequences of eukaryotic mRNAs, derived(More)
Nuclear hormone receptors are an abundant class of ligand-activated transcriptional regulators, found in varying numbers in all animals. Based on our experience of managing the official nomenclature of nuclear receptors, we have developed NUREBASE, a database containing protein and DNA sequences, reviewed protein alignments and phylogenies, taxonomy and(More)
Nuclear hormone receptors are an abundant class of ligand activated transcriptional regulators, found in varying numbers in all animals. Based on our experience of managing the official nomenclature of nuclear receptors, we have developed NUREBASE, a database containing protein and DNA sequences, reviewed protein alignments and phylogenies, taxonomy and(More)
The study of ecological systems has generated deep interest in exploring the complexity of chaotic food chains. The role of chaos in ecosystems is not entirely understood. One approach to have a better comprehension of ecological chaos is by analyzing it in mathematical models of basic food chains. In this article it is considered a classical chaotic food(More)
We consider a dynamical model of cancer growth including three interacting cell populations of tumor cells, healthy host cells and immune effector cells. For certain parameter choice, the dynamical system displays chaotic motion and by decreasing the response of the immune system to the tumor cells, a boundary crisis leading to transient chaotic dynamics is(More)
Defective interfering (DI) viruses are thought to cause oscillations in virus levels, known as the 'Von Magnus effect'. Interference by DI viruses has been proposed to underlie these dynamics, although experimental tests of this idea have not been forthcoming. For the baculoviruses, insect viruses commonly used for the expression of heterologous proteins in(More)
Josep Sardanyés, 2, ∗ Carla Rodrigues, Cristina Januário, Nuno Martins, Gabriel Gil-Gómez, and Jorge Duarte 5 Complex Systems Lab, Parc de Recerca Biomèdica de Barcelona, Dr. Aiguader, 88. 08003 Barcelona, Spain Institut de Biologia Evolutiva, Pg. Maritim de la Barceloneta 37, 08003 Barcelona, Spain. ESTS Technology Superior School of Setubal, Department of(More)
Coevolution between two antagonistic species has been widely studied theoretically for both ecologically- and genetically-driven Red Queen dynamics. A typical outcome of these systems is an oscillatory behavior causing an endless series of one species adaptation and others counter-adaptation. More recently, a mathematical model combining a three-species(More)