Jorge Cabello

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We assessed the effects of chronic nasal continuous positive airway pressure (CPAP) therapy on lung function in a series of unselected patients with overlap syndrome, and we determined whether there were differences in the response induced by CPAP between hypercapnic (PaCO2 ≥ 45 mm Hg) and eucapnic patients with overlap syndrome. The study population(More)
CCD (charged coupled device) and CMOS imaging technologies can be applied to thin tissue autoradiography as potential imaging alternatives to using conventional film. In this work, we compare two particular devices: a CCD operating in slow scan mode and a CMOS-based active pixel sensor, operating at near video rates. Both imaging sensors have been operated(More)
In emission tomography, iterative statistical methods are accepted as the reconstruction algorithms that achieve the best image quality. The accuracy of these methods relies partly on the quality of the system response matrix (SRM) that characterizes the scanner. The more physical phenomena included in the SRM, the higher the SRM quality, and therefore(More)
AIM To accurately quantify the radioactivity concentration measured by PET, emission data need to be corrected for photon attenuation; however, the MRI signal cannot easily be converted into attenuation values, making attenuation correction (AC) in PET/MRI challenging. In order to further improve the current vendor-implemented MR-AC methods for absolute(More)
UNLABELLED Attenuation correction (AC) is a critical requirement for quantitative PET reconstruction. Accounting for bone information in the attenuation map (μ map) is of paramount importance for accurate brain PET quantification. However, to measure the signal from bone structures represents a challenging task in MR. Recent (18)F-FDG PET/MR studies showed(More)
To assess the changes of intradiscal pressure at the bridged and at the adjacent levels to a lumbar two-level hybrid instrumentation. The elimination of motion produced by spinal fusion may have potential consequences beyond the index level overloading the juxtaposed spinal motion segments and leading to the appearance of degenerative changes. Degeneration(More)
A wide variety of digital alternatives have been presented to replace traditional film emulsion as detection medium in βAutoradiography. The main claim of most of the alternatives is higher sensitivity. On the other hand, spatial resolution remains the main problem to solve to be able to offer a sensible alternative to film. Solid state detectors, mainly(More)
This paper reports on a further development of an image simulation chain, and in particular, the inclusion of contrast degradation across an image using scatter to primary ratios calculated using Monte Carlo simulation. The Monte Carlo technique, using the Geant4 toolkit, has been implemented to model the scatter conditions when imaging the CDMAM phantom(More)
Statistical iterative methods are a widely used method of image reconstruction in emission tomography. Traditionally, the image space is modelled as a combination of cubic voxels as a matter of simplicity. After reconstruction, images are routinely filtered to reduce statistical noise at the cost of spatial resolution degradation. An alternative to produce(More)
The combination of Positron Emission Tomography (PET) with magnetic resonance imaging (MRI) in hybrid PET/MRI scanners offers a number of advantages in investigating brain structure and function. A critical step of PET data reconstruction is attenuation correction (AC). Accounting for bone in attenuation maps (μ-map) was shown to be important in brain PET(More)