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This paper presents a mathematical-computational toy model based on the assumed dynamic principles of prebiotic peptide evolution. Starting from a pool of amino acid monomers, the model describes in a generalized manner the generation of peptides and their sequential information. The model integrates the intrinsic and dynamic key elements of the initiation… (More)

We study oscillation death (OD) in a well-known coupled-oscillator system that has been used to model cardiovascular phenomena. We derive exact analytic conditions that allow the prediction of OD through the two known bifurcation routes, in the same model, and for different numbers of coupled oscillators. Our exact analytic results enable us to generalize… (More)

- Carlos Polanco, Thomas Buhse, José Lino Samaniego, Jorge Alberto Castañón González, Miguel Arias Estrada
- Acta biochimica Polonica
- 2014

In accordance with the second law of thermodynamics, the Universe as a whole tends to higher entropy. However, the sequence of far-from-equilibrium events that led to the emergence of life on Earth could have imposed order and complexity during the course of chemical reactions in the so-called primordial soup of life. Hence, we may expect to find… (More)

The thermal [4+2] cycloadditions of 3-acetyl-, 3-carbamoyl, and 3-ethoxycarbonylcoumarins with 2,3-dimethyl-1,3-butadiene under solvent free conditions are reported, as well as the epoxidation reactions of some adducts. Discussion is focused on the structural features of the Diels-Alder adducts and their epoxides, based upon NMR, X-ray, and mass spectral… (More)

- Jorge A González, Jose J Suárez, Vargas, Aneta Stefanovska, Peter V E Mcclintock
- 2015

We present a model of the cardiovascular system (CVS) based on a system of coupled oscillators. Using this approach we can describe several complex physiological phenomena that can have a range of applications. For instance, heart rate variability (HRV), can have a new deterministic explanation. The intrinsic dynamics of the HRV is controlled by… (More)

This work attempts to rationalize the possible prebiotic profile of the first dipeptides of about 4 billion years ago based on a computational discrete dynamic system that uses the final yields of the dipeptides obtained in Rode's experiments of salt-induced peptide formation (Rode et al., 1999, Peptides 20: 773-786). The system built a prebiotic scenario… (More)

- Mónica A García, Nustes, Emilio Hernández-García, Jorge A González, Mónica A Garcia, Emilio Nustes +2 others
- 2014

A universal differential equation is a nontrivial differential equation the solutions of which approximate to arbitrary accuracy any continuous function on any interval of the real line. On the other hand, there has been much interest in exactly solvable chaotic maps. An important problem is to generalize these results to continuos systems. Theoretical… (More)

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