Learn More
Field mice of the genus Calomys are small, mostly granivorous rodents common to several habitats in South America. To date, phylogenies for the genus have been proposed on the basis of morphological, chromosomal, and biochemical data, often with contradictory results due to incomplete species sampling or methodological shortcomings. In this paper, we(More)
In the probing theatrical opus " Jumpers, " one of the characters created by playwright Tom Stoppard (1972) asks the question: " Is God? " The question is thus phrased, the character explains, because to phrase it in any other way would presuppose an assumption of doubt on the part of the questioner, when in fact an unbiased mind and question is what is(More)
With about 400 living species and 82 genera, rodents of the subfamily Sigmodontinae comprise one of the most diverse and more broadly distributed Neotropical mammalian clades. There has been much debate on the origin of the lineage or the lineages of sigmodontines that entered South America, the timing of entrance and different aspects of further(More)
Transferrin receptor 1 (TfR1) is a cellular receptor for the New World hemorrhagic fever arenaviruses Machupo (MACV), Junín (JUNV), and Guanarito (GTOV). Each of these viruses is specifically adapted to a distinct rodent host species, but all cause human disease. Here we compare the ability of these viruses to use various mammalian transferrin receptor 1(More)
Habitat fragmentation and diversity loss due to increased conversion of natural habitats to agricultural uses influence the distribution and abundance of wildlife species and thus may change the ecology of pathogen transmission. We used hantaviruses in Panama as a research model to determine whether anthropogenic environmental change is associated with(More)
Zoonoses within wild reservoir host populations often occur focally obeying Pavlovskii's rules of "natural nidality". What appears to be a clear example is Bolivian hemorrhagic fever (BHF), a disease endemic to northeastern Bolivia. The etiological agent is Machupo virus (MACV, Arenaviridae). The vertebrate reservoir, identified 30 years ago, was Calomys(More)
Here, we present a comprehensive phylogenetic analysis based on nuclear and mitochondrial DNA sequences of rodents of the subfamily Sigmodontinae. The emphasis is placed on the large tribe Phyllotini; sampling includes for the first time in any molecular-based phylogenetic analysis representatives of several genera traditionally considered to be(More)
Centro Nacional Patagónico, Casilla de Correo 128, 9120 Puerto Madryn, Chubut, Argentina (UFJP, PT) Museu de Zoologia, Departamento de Biologia Animal, Universidade Federal de Viçosa, 36571-000 Viçosa, Minas Gerais, Brasil (GL) Department of Biological Sciences, Texas Tech University, Lubbock, TX 79409, USA (JSB) Museu de Ciências Naturais da Pontifı́cia(More)
Hantavirus cardiopulmonary syndrome (HCPS), which is caused by infection with Choclo virus, is uncommon in Panama, yet seropositivity among rural residents is as high as 60%. To clarify the environmental risk factors favoring rodent-to-human transmission, we tested serum from 3,067 rodents captured over a five-year period for antibodies against recombinant(More)