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STUDY OBJECTIVES In patients with moderate-to-severe COPD, an encouraged 6-min walking test (6MWT) is a high-intensity submaximal exercise protocol that shows an oxygen uptake (Vo(2)) plateau after the third minute of the test. This last feature prompted the hypothesis that self-paced walking speed is set to achieve "maximal" sustainable Vo(2), namely(More)
The present study was undertaken to test whether endurance training in patients with COPD, along with enhancement of muscle bioenergetics, decreases muscle redox capacity as a result of recurrent episodes of cell hypoxia induced by high intensity exercise sessions. Seventeen patients with COPD (FEV(1), 38 +/- 4% pred; PaO2), 69 +/- 2.7 mm Hg; PaCO2, 42 +/-(More)
The etiology of osteochondritis dissecans and the results of treating the early stages with arthroscopic fixation using cannulated screws is discussed. Arthroscopic surgery was performed on 14 patients with osteochondritis dissecans, and the osteochondral fragment was fixed with one or two screws. A second arthroscopic procedure was necessary to assess the(More)
The 6-min walking test (6MWT) is frequently used to assess functional capacity in chronic cardiopulmonary disorders because of its simplicity. The study examines the physiological responses during encouraged 6MWT in patients with chronic obstructive pulmonary disease. Pulmonary oxygen (O2) uptake (V'O2) was measured in 20 male patients (age 66+/-6 yrs,(More)
BACKGROUND A physiological increase in muscle glutathione after training is not seen in patients with chronic obstructive pulmonary disease (COPD), indicating abnormal peripheral muscle adaptations to exercise. OBJECTIVE We hypothesized that oxidative stress is primarily associated with low body mass index (BMI). METHODS Eleven patients with preserved(More)
STUDY DESIGN Cross-sectional. OBJECTIVE To assess cough using air stacking (AS) to assist inspiratory volume with abdominal compression (AC) during expiration in patients with American Spinal Injury Association Impairment Scale (AIS) A. SETTING Large tertiary hospital in Chile. METHODS Peak cough flow (PCF) was measured during four different(More)
STUDY OBJECTIVE To determine whether standard clinical and transthoracic echocardiographic criteria considered to be suggestive of the presence of endocarditis-associated paravalvular abscess are predictive of which patients would benefit from reliable but invasive transesophageal echocardiographic investigations for abscess. DESIGN Retrospective chart(More)
BACKGROUND AND OBJECTIVE Exercise limitation is a common finding in chronic obstructive pulmonary disease (COPD) patients and has an important role in disease prognosis and the use of health care services. There are no questionnaires in Spanish language that evaluate the impact of the disease in the activities of daily living in these patients. Our(More)
OBJECTIVES We investigated the effects of two different types of manual rib cage compression on expiratory flow and mucus clearance during prolonged mechanical ventilation in pigs. DESIGN Prospective randomized animal study. SETTING Animal research facility, University of Barcelona, Spain. SUBJECTS Nine healthy pigs. MEASUREMENT AND MAIN RESULTS(More)
Pulmonary hypertension is a serious complication of chronic obstructive pulmonary disease (COPD) that currently has no established pharmacological treatment. This study aimed to assess whether concomitant treatment with sildenafil would enhance the results of pulmonary rehabilitation in patients with COPD and increased pulmonary arterial pressure (PAP). In(More)