Jordan Gaines

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Over the last 15years, many studies have established an association of sleep apnea with inflammation and metabolic aberrations. However, no controlled studies have examined potential gender effects in this association. We recruited 120 middle-aged, predominantly non-obese mild-to-moderate sleep apneics and controls (62 males, 58 females). All participants(More)
STUDY OBJECTIVES To examine whether insomnia is associated with spectral electroencephalographic (EEG) dynamics in the beta (15-35Hz) range during sleep in an adolescent general population sample. METHODS A case-control sample of 44 adolescents from the Penn State Child Cohort underwent a 9-h polysomnography, clinical history and physical examination. We(More)
Obstructive sleep apnoea (OSA) is a prevalent sleep disorder characterized by upper airway obstruction during sleep, resulting in intermittent breathing pauses despite effort, reduced blood oxygen saturation, hypo-xia and arousals. With prevalence in the general population estimated at 17–24% of men and 5–9% of women (Young et al. been linked to the key(More)
Inflammation has been suggested as a potential pathway by which insomnia and short sleep can affect risk of morbidity in adults. However, few studies have examined the association of insomnia with inflammation in adolescents, despite accumulating evidence that pathophysiologic changes may already occur during this critical developmental period. The present(More)
Based on previous studies on the role of objective sleep duration in predicting morbidity in individuals with insomnia, we examined the role of objective sleep duration in differentiating behavioral profiles in adolescents with insomnia symptoms. Adolescents from the Penn State Child Cohort (n = 397, ages 12-23, 54.7% male) underwent a nine-hour(More)
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