Joong-Uhn Choi

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OBJECTIVES The purpose of this retrospective study was to evaluate causes contributing to surgical resectability and seizure outcomes depending on various clinical and surgical factors. PATIENTS AND METHODS The records of 44 patients with gangliogliomas surgically treated between April 1986 and March 2007, were retrospectively reviewed to assess(More)
CASE REPORT A 17-month-old infant girl was admitted with complex partial seizures and right side hemiparesis. Five days after the last seizure, MR signal changes were observed in the left hemisphere with a cavernous hemangioma in the middle temporal gyrus. However, these MR signal changes had normalized 11 days after the last seizure, except for the(More)
Cerebral abscess results in an extensive capsular formation, which is an important limiting barrier for the spread of microorganism. Reactive astrocytes and endothelial cells are major cellular components of the abscess capsule together with fibrocytes. Molecular pathogenesis that results in the migration and proliferation of these cells remain speculative.(More)
OBJECT The authors propose that anterior callosotomy -- thought to have some advantages over total callosotomy -- is not superior to total callosotomy for prevention of seizure propagation or other complications. METHODS The study comprised 34 patients in whom generalized epilepsy syndrome or frontal lobe seizures with a secondary generalization were(More)
Recent evidence has demonstrated associations between the single nucleotide polymorphism (SNP) rs11614913 in miR-196a2C>T and various pathologies. A main target of miRNA-196a is annexin A1 (lipocortin1, ANXA1), which is associated with increased multiple malignant tumors in brain models of ischemia and reperfusion injury. To determine the effects of miRNA(More)
OBJECTS We designed several distraction devices and applied these instruments in 14 patients with varying types of craniosynostosis. The aim of this report is to clarify the advantages and disadvantages of these surgical methods and to discuss current concepts for the surgical strategy in the treatment of craniosynostosis. METHODS From January 2000 to(More)
OBJECT The aim of this study was to determine the risk factors associated with the development of postoperative ischemic complications after surgical revascularization used to treat pediatric patients with ischemic moyamoya disease. METHODS The clinical, imaging, and perioperative data from 170 procedures in 90 children who underwent indirect(More)
Although intractable epilepsy associated with hypothalamic hamartoma (HH) can be controlled by microsurgical resection of the lesion, excision of deep-seated lesions is often associated with morbidity and mortality. Endoscopic disconnection is less invasive and seems to be well suited for this indication. The authors discuss the role of endoscopic-assisted(More)
BACKGROUND AND PURPOSE Encephaloduroarteriosynangiosis (EDAS) has become the main treatment for moyamoya disease, a chronically progressive cerebrovascular occlusive disease in children. We aimed to assess the utility of perfusion-weighted MR imaging for evaluating hemodynamic changes before and after EDAS. METHODS Thirteen patients with angiographically(More)
BACKGROUND It is well known that selective posterior rhizotomy is effective for relieving spasticity associated with cerebral palsy. However, there is significant variation between surgeons in terms of how much and which of the posterior rootlets should be cut for the improvement of ambulatory function without causing adverse effects. METHODS The study(More)