Joona Rouvinen

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The enzymatic degradation of cellulose is an important process, both ecologically and commercially. The three-dimensional structure of a cellulase, the enzymatic core of CBHII from the fungus Trichoderma reesei reveals an alpha-beta protein with a fold similar to but different from the widely occurring barrel topology first observed in triose phosphate(More)
Video coding standards, such as MPEG-4, H.264, and VC1, define hybrid transform based block motion compensated techniques that employ almost the same coding tools. This observation has been a foundation for defining the MPEG Reconfigurable Multimedia Coding framework that targets to facilitate multi-format codec design. The idea is to send a description of(More)
Selected 20-epi and 20-normal vitamin D(3) analogs were studied. First, point mutations were introduced into human vitamin D receptor (VDR) to identify residues important for ligand binding. In helices three, four and five, His229, Asp232, Ser237 and Arg274 seem to have an important role in the binding of calcitriol. Surprisingly, the 20-epi analog MC 1288(More)
Practically all modern video coding standards such as H.264, MPEG-4 and VC-1 are based on hybrid transform based block motion compensated techniques, that employ almost the same coding tools. The same approach is used with numerous non-standard proprietary codecs, with decoders available via Internet as browser plugins. For mobile devices power efficient(More)
A peptide of 27 amino acids, VDR(102-76), representing residues 76-102 immediately C-terminal to the second Zn finger of human vitamin D receptor (hVDR) was conjugated to fluorescein-labelled IgG using a bifunctional coupling reagent, m-maleimidobenzoyl n-hydroxysuccinimide. Upon microinjection into the cytoplasm of human osteosarcoma MG-63 cells, the(More)
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