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The kainoids are a class of excitatory and excitotoxic pyrrolidine dicarboxylates that act at ionotropic glutamate receptors. The kainoids bind kainate receptors with high affinity and, while binding affinity is lower at AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptors, they are active in functional assays at this receptor subtype(More)
We present models and measurements of lightly-doped and heavily-doped dual ring/dual-bar and double-ended tuning fork (DETF) resonators. Both models and measurements indicate that the Q of these resonators is only slightly impacted by the doping level, despite being dominated by thermoelastic dissipation (TED), which has a strong dependence on(More)
Homology models of the ionotropic rat kainate receptor iGluR6, based on the ligand binding domains of iGluR2, were constructed. A systematic analysis by low-mode docking searches of kainic acid in homology models of the native iGluR6 receptor, chimeric (iGluR2 and iGluR6) receptors and mutant receptors have identified three residues which influence the(More)
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