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The Impact of the Gut Microbiota on Humoral Immunity to Pathogens and Vaccination in Early Infancy

• Quang N Nguyen, Jonathon E. Himes, David Roldán Martínez, Sallie R. Permar
• PLoS pathogens
• 2016

1 Duke Human Vaccine Institute, Duke University School of Medicine, Durham, North Carolina, United States of America, 2 Department of Molecular Genetics and Microbiology, Duke University School of… (More)

Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission.

• Qihua Fan, Cody S. Nelson, +15 authors Sallie R. Permar
• Clinical and vaccine immunology : CVI
• 2017

Human cytomegalovirus (HCMV) is the most common congenital infection worldwide and the leading infectious cause of neurologic deficits and hearing loss in newborns. Development of a maternal HCMV… (More)

Rapid Development of gp120-Focused Neutralizing B Cell Responses during Acute Simian Immunodeficiency Virus Infection of African Green Monkeys.

• Joshua D. Amos, Jonathon E. Himes, +8 authors Sallie R. Permar
• Journal of virology
• 2015

UNLABELLED The initial phases of acute human immunodeficiency virus type 1 (HIV-1) infection may be critical for development of effective envelope (Env)-specific antibodies capable of impeding the… (More)

Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus

• Ruijun Zhang, David Roldán Martínez, +18 authors Sallie R. Permar
• Nature communications
• 2016

African green monkeys (AGMs) are natural primate hosts of simian immunodeficiency virus (SIV). Interestingly, features of the envelope-specific antibody responses in SIV-infected AGMs are distinct… (More)

Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized in Plasma and Milk in Chronically Infected African Green Monkeys.

• Jonathon E. Himes, Carrie Ho, +9 authors Sallie R. Permar
• Journal of virology
• 2016

UNLABELLED Unlike human immunodeficiency virus type 1 (HIV-1)-infected humans, African-origin, natural simian immunodeficiency virus (SIV) hosts, such as African green monkeys (AGMs), sustain… (More)

Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys

• Jonathon E. Himes, Ria Goswami, +17 authors Sallie R. Permar
• Mucosal Immunology
• 2018

Breast milk HIV-1 transmission is currently the predominant contributor to pediatric HIV infections. Yet, only ~10% of breastfeeding infants born to untreated HIV-infected mothers become infected.… (More)

Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys

• Quang N Nguyen, David Roldán Martínez, +10 authors Sallie R. Permar
• Retrovirology
• 2018

The initial envelope (Env)-specific antibody response in acutely HIV-1-infected individuals and simian immunodeficiency virus (SIV)-infected rhesus monkeys (RMs) is dominated by non-neutralizing… (More)

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