Jonathan T. Davies

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A method to rapidly generate gene replacement constructs by fusion PCR is described for Aspergillus nidulans. The utility of the approach is demonstrated by green fluorescent protein (GFP) tagging of A. nidulans ndc80 to visualize centromeres through the cell cycle. The methodology makes possible large-scale GFP tagging, promoter swapping, and deletion(More)
Chemical ozone destruction occurs over both polar regions in local winter-spring. In the Antarctic, essentially complete removal of lower-stratospheric ozone currently results in an ozone hole every year, whereas in the Arctic, ozone loss is highly variable and has until now been much more limited. Here we demonstrate that chemical ozone destruction over(More)
*As counted by MS Word 'word count' command. This includes all of the body of the report but none of the other appendices. Abstract As organisations increasingly rely on geographically dispersed workforces there is an emerging need to collaborate on projects that span distributed teams and different time frames. This includes a need for collaboration in the(More)
We have developed spotted cell microarrays for measuring cellular phenotypes on a large scale. Collections of cells are printed, stained for subcellular features, then imaged via automated, high-throughput microscopy, allowing systematic phenotypic characterization. We used this technology to identify genes involved in the response of yeast to mating(More)
The 2011 meeting of the European Ecological Federation took place in Ávila, Spain, from 26th September to 29th September. The French Ecological Society (SFE) and the Foundation for Research on Biodiversity (FRB) sponsored a session entitled 'Evolutionary history, ecosystem function and conservation biology: new perspectives'. We report on the main insights(More)
The tinA gene of Aspergillus nidulans encodes a protein that interacts with the NIMA mitotic protein kinase in a cell cycle-specific manner. Highly similar proteins are encoded in Neurospora crassa and Aspergillus fumigatus. TINA and NIMA preferentially interact in interphase and larger forms of TINA are generated during mitosis. Localization studies(More)
Determining the factors that influence the transmission of parasites among hosts is important for directing surveillance of animal parasites before they successfully emerge in humans, and increasing the efficacy of programs for the control and management of zoonotic diseases. Here we present a review of recent advances in the study of parasite sharing,(More)
In comparison with other operational risk management and measurement tools such as loss data (internal, public and consortium), risk-and-control assessments, capital allocation and performance measurement, key risk indicators (KRIs) remain one of the outstanding action items on most firms' to-do lists, along with scenario analysis. KRIs are not new, but, up(More)
OGSA-DAI has been developing Grid middleware for over two years now. A high profile project within the Grid community OGSA-DAI is increasingly being used by Grid based projects to provide their Data Access and Integration (DAI) requirements. From a simple set of services relatively sophisticated usage scenarios may be realised. This presentation examines a(More)
5 and Wim van Driel 6 ABSTRACT VIRGOHI21 is an H i source detected in the Virgo Cluster survey of Davies et al. (2004) which has a neutral hydrogen mass of 10 8 M ⊙ and a velocity width of ∆V 20 = 220 km s −1. From the Tully-Fisher relation, a galaxy with this velocity width would be expected to be 12th magnitude or brighter; however deep CCD imaging has(More)