Jonathan R Bates

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The BALB/c mouse primary epidermal cell culture sys tem is currently being developed as a model system for chemical carcinogenesis studies with the immediate aims of achieving a high incidence of chemically induced trans formation and developing rapid assays fortumorigenicity. Primary cultures treated with N-methyl-(V -nitro-N-nitrosoguanidine (1 to 2(More)
OBJECTIVES We investigated the patterns of perfusion and metabolism in dysfunctional myocardium whose contractility improved with dobutamine. BACKGROUND Clinical studies have suggested that dobutamine echocardiography can identify hibernating myocardium, but laboratory studies suggest that reduced perfusion limits the response to dobutamine. METHODS(More)
We validated a novel method for screening Escherichia coli resistance to antibiotics in environmental samples using modified Difco MI agar (Becton Dickinson) impregnated with selected antibiotics (tetracycline, ampicillin, cephalexin, and sulfamethoxazole), termed MI-R. This method combines an existing rapid assessment technique for E. coli enumeration with(More)
Rotational scanning from the subxiphoid position is an image acquisition technique used for reconstruction of dynamic three-dimensional echocardiographic images in infants and small children. The orientation of the heart within the three-dimensional data set is variable and dependent on the image plane at which rotational scanning was initiated. We describe(More)
The purpose of this study was to examine the ability of dobutamine stress echocardiography to stratify patients with juvenile onset, insulin-dependent diabetes mellitus who are being considered for kidney and/or pancreas transplantation, into high-or low-risk groups for future cardiac events. Fifty-three such patients underwent dobutamine stress(More)
Dynamic three-dimensional echocardiographic reconstructions of 27 cardiac septation defects were performed in 19 sedated infants and children. Using a subxiphoid rotational scanning approach, complete visualization of the entire shape and breadth of the defect was attained in 11 of 16 ventricular septal defects and 9 of 11 atrial septal defects. This(More)
Color coding is a new software application for digitized echocardiograms that displays a reference image of end diastole throughout the cardiac cycle. With color-coded digitized echocardiograms, we determined the frequency of, and corrected for cardiac translation in 21 bicycle stress echocardiograms in patients who were known to be without significant(More)
OBJECTIVE To determine if 1) patients have distinct affective reaction patterns to medication information, and 2) whether there is an association between affective reaction patterns and willingness to take medication. METHODS We measured affect in real time as subjects listened to a description of benefits and side effects for a hypothetical new(More)
A spayed Cocker Spaniel with idiopathic chronic generalized seborrhea responded poorly to treatment, consisting of medicated baths and intermittent use of lincomycin and triamcinolone acetate, over a 5 1/2-year period. At 7 years of age, the animal became refractory to triamcinolone injections. Oral vitamin A therapy was not beneficial, but oral use of(More)
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