Jonathan McGhie

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NHIK 3025 cells derived from a carcinoma in situ were exposed to hematoporphyrin derivative (Hpd) and light and examined by light microscopy, freeze-etching, scanning, and transmission electron microscopy. The first morphologic changes observed were shrinkage of mitochondria and formation of vesicles on the cell membrane. Furthermore, increased membrane(More)
AIMS Slaughterhouse and on-farm surveys were undertaken to investigate some aspects of leptospirosis (Leptospira interrogans) in farmed deer in the lower North Island of New Zealand. METHODS Blood samples and kidneys were collected at slaughter from 601 l-year and older red and red X Wapiti stags and 21 adult hinds from 53 farms (10 or 12 deer per farm).(More)
BACKGROUND Intrathecal drug delivery is known to be effective in alleviating cancer pain in patients for whom the conventional World Health Organization approach has proved insufficient. A multidisciplinary interventional cancer pain service was established in the West of Scotland in 2008 with the aim of providing a safe and effective intrathecal drug(More)
Induction of DNA strand breaks by a short electron pulse (18.5 Gy) and the subsequent strand-break rejoining were investigated at hyperthermia (42.5 and 45 degrees C) and at 37 degrees C during irradiation and repair. The cells were irradiated immediately after 2.5 min equilibration (i.e., from 37 to 42.5 or 45 degrees C) to investigate the effect of(More)
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