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PURPOSE To report a computerized method for determining visual acuity in children using the Amblyopia Treatment Study visual acuity testing protocol. METHODS A computerized visual acuity tester was developed that uses a programmed handheld device that uses the Palm operating system (Palm, Inc, Santa Clara, California). The handheld device communicates(More)
PURPOSE We developed a near ocular dominance test modeled after the distance hole-in-the-card test and assessed both test-retest reliability of four tests of ocular dominance and agreement between tests. METHODS Forty-six subjects aged 18 to 78 years with visual acuity 20/40 or better in each eye were enrolled from a primary care practice. All subjects(More)
PURPOSE To assess the test-retest reliability of the electronic Early Treatment Diabetic Retinopathy Study (E-ETDRS) visual acuity algorithm using the computerized Electronic Visual Acuity (EVA) tester in children 7 to <13 years old. DESIGN Test-retest reliability study. METHODS This multicenter study involved 245 subjects at four clinical sites. As the(More)
OBJECTIVE To compare full-time patching (all hours or all but 1 hour per day) to 6 hours of patching per day, as prescribed treatments for severe amblyopia in children younger than 7 years. DESIGN Prospective, randomized multicenter clinical trial (32 sites). PARTICIPANTS One hundred seventy-five children younger than 7 years with amblyopia in the range(More)
PURPOSE To determine factors associated with pretreatment and posttreatment stereoacuity in subjects with moderate anisometropic amblyopia. METHODS Data for subjects enrolled in seven studies conducted by the Pediatric Eye Disease Investigator Group were pooled. The sample included 633 subjects aged 3 to <18 years with anisometropic amblyopia, no(More)
PURPOSE To determine the effect of induced monocular blur on stereoacuity measured with real depth and random dot tests. METHODS Monocular visual acuity deficits (range, 20/15 to 20/1600) were induced with 7 different Bangerter filters (<0.1, 0.1, 0.2, 0.3, 0.4, 0.8, and 1.0) in 15 visually normal adults. Stereoacuity was measured with Frisby and Frisby(More)
BACKGROUND We prospectively evaluated the performance of three stereoacuity tests in patients with a wide range of strabismus angles to determine the maximum angle of horizontal strabismus consistent with true stereopsis as well as the extent of false-positive results. METHODS Subjects age > or = 5 years old (n = 186) with constant horizontal strabismus(More)
PURPOSE To develop a presentation protocol for the new Frisby-Davis 2 (FD2) distance stereoacuity test. DESIGN Prospective data collection. METHODS Stereoacuity was tested monocularly and binocularly in 95 patients with a variety of strabismic and nonstrabismic conditions, using the FD2, employing a modified staircase procedure. The Preschool Randot(More)
PURPOSE The method of counting cell nuclei above the internal limiting membrane in histologic sections is considered the standard when quantifying neovascularization (NV) in rodent oxygen-induced retinopathy (OIR). An alternative, more rapid method of counting clock hours in flatmounted adenosine diphosphatase (ADPase)-stained rat retinas is analogous to(More)
In a prospective, population-based cohort study, the authors investigated the effect of in-utero exposure to maternal smoking and consumption of alcohol, coffee, and tea on the risk of strabismus. They reviewed medical records for children in the Danish National Birth Cohort identified through national registers as possibly having strabismus. Relative risk(More)