Jonathan M. Chambers

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Individuals with Parkinson's disease (PD) show marked impairments in their ability to generate self-initiated, or "voluntary", saccadic eye movements. Investigations of visually guided, or "reflexive", saccades have, on the other hand, produced inconclusive results with studies showing response times (RTs) in persons with PD that are slower, faster, or(More)
We present an application of a massively parallel processor array VLSI circuit to the implementation of neural networks in complex architectural arrangements. The work was motivated by existing biologically plausible models of a set of sub-cortical nuclei -the basal ganglia. The model includes 5 layers, each consisting of 16384 leaky integrator neurons,(More)
Computational modellers are becoming increasingly interested in building large, eclectic, biological models. These may integrate nervous system components at various levels of description, other biological components (e.g. muscles), non-biological components (e.g. statistical discriminators or control software) and, in embodied modelling, even hardware(More)
Introduction In the visual system, attending to important objects in the visual field relies on the transfer of top-down, objectbased task information to the spatially organised areas of cortex. How this occurs and the method by which this information can influence the dorsal stream and redirect gaze are not well understood. Current models of the ventral(More)
to aids when covariates are measured with error. (1992) Fault and cause diagnosis of casting defects: a case study. (1993) Fault and cause diagnosis of casting defects: case study No. 2. Quality and Reliability Engineering International 9, pp 15{27. 16 some valid inference about the remaining terms. There is however scope for further work with this class of(More)
Analysing complex scenes in detail over wide visual fields requires massive computational resources when performed in parallel. One solution to this problem, used in primates, is active vision. Here detailed analysis is concentrated at a central, foveal, area, while more peripheral areas receive only sufficient analysis to detect phasic stimuli and(More)
The basal ganglia (BG) are a group of subcortical nuclei which are believed to be involved in mediating action selection [1]. They are arranged in a series of topographically organised anatomical ‘loops,’ receiving input from large regions of cortex, and projecting back to the same cortical regions via thalamus. These basal gangliathalamocortical (BGTC)(More)
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