Jonathan M. Chambers

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Individuals with Parkinson's disease (PD) show marked impairments in their ability to generate self-initiated, or "voluntary", saccadic eye movements. Investigations of visually guided, or "reflexive", saccades have, on the other hand, produced inconclusive results with studies showing response times (RTs) in persons with PD that are slower, faster, or(More)
We present an application of a massively parallel processor array VLSI circuit to the implementation of neural networks in complex architectural arrangements. The work was motivated by existing biologically plausible models of a set of sub-cortical nuclei -the basal ganglia. The model includes 5 layers, each consisting of 16384 leaky integrator neurons,(More)
— Computational modellers are becoming increasingly interested in building large, eclectic, biological models. These may integrate nervous system components at various levels of description, other biological components (e.g. muscles), non-biological components (e.g. statistical discriminators or control software) and, in embodied modelling, even hardware(More)
2. An endogenous neuronal process? Growing neurophysiological evidence indicates that during decision making single neurons can integrate the sensory evidence in favour of a particular response. Mathematical models can describe the dynamics of this evidence accumulation process (Ratcliff et al, 2003; Reddi & Carpenter, 2000) and promise to connect the(More)
Intestinal digestive and absorptive function and the gross and histologic appearance of the gastrointestinal tract were evaluated in Basenji dogs with chronic diarrhea, asymptomatic Basenji dogs, and healthy control dogs. Gastric rugal hypertrophy, lymphocytic gastritis, and gastric mucosal atrophy occurred in asymptomatic and affected Basenji dogs. All(More)
— Analysing complex scenes in detail over wide visual fields requires massive computational resources when performed in parallel. One solution to this problem, used in primates , is active vision. Here detailed analysis is concentrated at a central, foveal, area, while more peripheral areas receive only sufficient analysis to detect phasic stimuli and(More)
Congenital asymmetric development, resulting in a small right thoracic limb, was diagnosed in a dog. The limb was anatomically normal. The lesion closely resembled hemiatrophy. Congenital asymmetric development should be considered in the differential diagnosis of limb length discrepancies. Treatment is required only in cases of extreme discrepancy between(More)