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  • Paul M. Zeltzer, James M. Boyett, +13 authors Roger J. Packer
  • Medicine
  • Journal of clinical oncology : official journal…
  • 1999 (First Publication: 1 March 1999)
  • PURPOSE From 1986 to 1992, "eight-drugs-in-one-day" (8-in-1) chemotherapy both before and after radiation therapy (XRT) (54 Gy tumor/36 Gy neuraxis) was compared with vincristine, lomustine (CCNU),Expand
  • I. Pollack, R. Hamilton, +5 authors J. Finlay
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2006 (First Publication: 20 July 2006)
  • PURPOSE O6-methylguanine-DNA methyltransferase (MGMT) functions to counteract the cytotoxic effects of alkylating agents, such as nitrosoureas, which play a central role in the treatment of childhoodExpand
  • Jonathan L Finlay, James M. Boyett, +7 authors Melvin Tefft
  • Medicine
  • Journal of clinical oncology : official journal…
  • 1995
  • PURPOSE In a previous randomized trial, the addition of adjuvant chemotherapy to postoperative radiotherapy proved beneficial in the treatment of childhood high-grade astrocytomas. The present studyExpand
  • A. Villani, A. Shore, +13 authors D. Malkin
  • Medicine
  • The Lancet. Oncology
  • 2016 (First Publication: 1 September 2016)
  • BACKGROUND Carriers of a germline TP53 pathogenic variant have a substantial lifetime risk of developing cancer. In 2011, we did a prospective observational study of members of families who chose toExpand