Jonathan Kirsch

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The need for communication privacy over public networks is of growing concern in today’s society. As a result, privacy-preserving authentication and key exchange protocols have become critical primitives in building secure distributed systems. Secret handshakes provide such a service by allowing two members of the same group to secretly and privately(More)
We describe a load-balancing mechanism for assigning elements to servers in a distributed data structure that supports range queries. The mechanism ensures both load-balancing with respect to an arbitrary load measure specified by the user and geographical locality, assigning elements with similar keys to the same server. Though our mechanism is(More)
A 93 kd polypeptide associated with the mammalian inhibitory glycine receptor (GlyR) is localized at central synapses and binds with high affinity to polymerized tubulin. This protein, named gephyrin (from the Greek gamma epsilon phi upsilon rho alpha, bridge), is thought to anchor the GlyR to subsynaptic microtubules. Here we report its primary structure(More)
Existing Byzantine-resilient replication protocols satisfy two standard correctness criteria, safety and liveness, in the presence of Byzantine faults. In practice, however, faulty processors can, in some protocols, significantly degrade performance by causing the system to make progress at an extremely slow rate. While ldquocorrectrdquo in the traditional(More)
Existing Byzantine-resilient replication protocols satisfy two standard correctness criteria, safety and liveness, even in the presence of Byzantine faults. The runtime performance of these protocols is most commonly assessed in the absence of processor faults and is usually good in that case. However, faulty processors can significantly degrade the(More)
The molybdenum cofactor (Moco), a highly conserved pterin compound complexing molybdenum, is required for the enzymatic activities of all molybdenum enzymes except nitrogenase. Moco is synthesized by a unique and evolutionarily old pathway that requires the activities of at least six gene products. Some of the proteins involved in bacterial, plant, and(More)
This paper presents the first hierarchical byzantine fault-tolerant replication architecture suitable to systems that span multiple wide-area sites. The architecture confines the effects of any malicious replica to its local site, reduces message complexity of wide-area communication, and allows read-only queries to be performed locally within a site for(More)
This paper presents an overview of Paxos for System Builders, a complete specification of the Paxos replication protocol such that system builders can understand it and implement it. We evaluate the performance of a prototype implementation and detail the safety and liveness properties guaranteed by our specification of Paxos.
This paper presents a complete specification of the Paxos replication protocol such that system builders can understand it and implement it. We evaluate the performance of a prototype implementation and detail the safety and liveness properties guaranteed by our specification of Paxos.
PURPOSE With the rising incidence of melanoma, more patients are undergoing surveillance for disease recurrence. Our purpose was to study levels of proteins that might be secreted in the blood of patients with metastatic melanoma that can be used for monitoring these individuals. METHODS Genome-wide gene expression data were used to identify abundantly(More)